Synthesis of Dihydro-1,2,4-Triazin-6-one Containing Nitroarginine Moiety

Bassam A Abu Thaher, Naser S El-Abadla, Reda M Abdel-Rahman, Khaled A EL- Nwairy


Nitrilimines (2), react with nitroarginine methyl ester (3) at room temperature, through cyclocondensation reaction, to give 1-aryl-3-substituted-1,2,4-triazin-6-ones (4a-k). The structure of these compounds was deduced from: elemental analysis, IR, mass spectra, 1H and 13C NMR.


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